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pharmacy collection
This product is available for collection at a Clicks pharmacy only.
dispensed by pharmacist
Dispensed at the professional discretion of a Clicks Pharmicist
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Detailed information
Description:
Strepsils Intensive Relief For Sore Throats 12 Lozenges
Detailed Description:
©2007 Reckitt Benckiser Pharmaceuticals (Pty) Ltd.
Consumer care line: 0861 11 11 00.
Indications:
Relief of pain of sore throats. For bacterial sore throat appropriate antibiotics should be prescribed.
Each lozenge contains: flurbiprofen 8.75 mg.
Observe dosage recommendations.
Scheduling status: S1.
Proprietary name and dosage form:
Strepsils® intensive lozenges.
Composition:
Each lozenge contains 8.75 mg flurbiprofen.
Pharmacological classification: A. 16 ear, nose and throat preparations.
Pharmacological action:
Pharmacodynamics: flurbiprofen is non-steroidal anti-inflammatory drug which has analgesic, antipyretic and anti-inflammatory properties. Flurbiprofen is an inhibitor of prostaglandin synthetase enzymes.
Pharmacokinetics: flurbiprofen is rapidly absorbed following the use of Strepsils intensive with plasma concentrations peaking at 30-40 minutes. Peak concentrations are achieved more rapidly than, but are of similar magnitude to, those achieved after an equivalent swallowed dose.
Flurbiprofen is rapidly distributed throughout the body. It is mainly metabolised by hydroxylation and excreted via the kidneys.
It is extensively bound to plasma proteins and has an elimination half-life of 3 to 6 hours.
Flurbiprofen is excreted in very small amounts in human milk (less than 0.05 microlitres per ml).
Indications: Strepsils Intensive is indicated for the relief of pain of sore throats. For bacterial sore throat appropriate antibiotics should be prescribed.
Identification:
A round, pale yellow to brown lozenge with a characteristic honey and lemon taste and the S-brand icon intagliated on both sides.
Presentation: cartons containing 12 blister packed lozenges.
Pack size:
1 Pack
Quantity in pack:
12
Marketing description:
S1.
Soothing relief for sore throats.
Strepsils®.
Intensive.
Flurbiprofen 8.75 mg.
12 lozenges.
Brand:
Strepsils
Package type:
Box
How to use
Usage instructions:
Directions: children and adults over 12 years.
Dissolve one lozenge slowly in the mouth, every 3 to 6 hours.
Please read leaflet before use.
Dosage and directions for use:
Adults and children over 12 years:
One lozenge sucked/dissolved slowly in the mouth every 3-6 hours as required. Maximum of 5 lozenges in a 24 hour period. It is recommended that this product should not be used for more than 3 days. If symptoms persist, talk to your doctor.
Children: not indicated for children under 12 years.
Elderly: no dose modification is required.
Storage instructions:
Store below 25 degrees C.
Store below 25 degrees C in a dry place, protected from light.
Warnings:
Contra-indications:
Hypersensitivity to flurbiprofen, aspirin or other NSAIDs. Existing or history of peptic ulceration. History of bronchospasm, rhinitis or urticaria associated with aspirin or other NSAIDs. Pregnancy and lactation. Children under the age of 12 years.
Use of NSAIDs during the third trimester of pregnancy may result in premature closure of the foetal ductus arteriosus in utero and persistent pulmonary hypertension of the newborn. Flurbiprofen appears in the breast milk.
To avoid local irritation, Strepsils intensive lozenges should be moved around the mouth whilst sucking.
Side effects and special precautions:
Side-effects: changes in taste sensation and paraesthesiae in the mouth are a common side effect. Dyspepsia, nausea, vomiting, gastrointestinal haemorrhage, diarrhoea, mouth ulcers, fluid retention and oedema may occur.
Urticaria, angioedema and rashes of varying description have been reported.
Very rarely jaundice and thrombocytopenia have been reported. These are usually reversible on withdrawal of the medicine. Very rarely aplastic anaemia and agranulocytosis have been reported in association with the use of flurbiprofen.
Undesirable effects may be diminished by using the minimum effective dose for the shortest possible duration.
Special precautions:
Bronchospasm may be precipitated in patients suffering from or with a previous history of bronchial asthma. Asthmatics and patients allergic to any other pain relievers should only take Strepsils intensive on the advice of a doctor.
NSAIDs have been reported to cause nephrotoxicity in various forms including interstitial nephritis, nephrotic syndrome and renal failure. In patients with renal, cardiac or hepatic impairment, caution is required since the use of NSAIDs may result in the deterioration of renal function. Caution is required in patients with hypertension.
Flurbiprofen can prolong bleeding time and caution is required in patients with a potential for abnormal bleeding (such as patients on anticoagulant therapy). Caution is advised in patients with bleeding disorders.
Strepsils intensive should not be taken with other NSAIDs.
Interactions:
Studies have shown that the diuretic response to furosemide can occasionally be reduced by flurbiprofen. Similarly, interference with the action of anticoagulants has occasionally been reported. Other studies failed to show any interaction between flurbiprofen and digoxin, tolbutamide or antacids. NSAIDs may diminish the effect of antihypertensive drugs.
Known symptoms of overdosage and particulars of its treatment:
Keep to the stated dose.
Symptoms of overdosage may include nausea, vomiting, headache, drowsiness, blurred vision and dizziness. Treatment should consist of gastric lavage and if necessary correction of serum electrolytes. There is no specific antidote to flurbiprofen.
Keep out of reach of children.