Storage instructions:
Store below 25 degrees C.

Warnings:
Contra-indications:Use of NSAID's is contra-indicated in patients with heart failure.Nurofen should not be given to patients with a history of gastrointestinal bleeding or perforation (PUBs) related to previous NSAID use. Active or history of recurrent ulcer, haemorrhage or perforations.Nurofen should not be given to patients with bleeding disorders, cardiovascular disease, peptic ulceration or a history of such ulceration. Asthma sufferers should only take Nurofen after consulting a doctor. Caution is advised in those patients who are receiving coumarin anticoagulants. Patients who are sensitive to aspirin should not be given Nurofen.Caution is required in patients with a history of hypertension and/or heart failure as fluid retention and oedema have been reported in association with NSAID therapy.Elderly: the elderly have an increased frequency of adverse reactions to NSAID's, especially gastrointestinal bleeding and perforation (PUBs) which may be fatal.The risk of gastrointestinal bleeding or perforation (PUBs) is higher with increasing doses of NSAID's, in patients with a history of ulcers, and the elderly.When gastrointestinal bleeding or ulceration occurs in patients receiving NSAID's, treatment with NSAID's should be stopped.NSAID's should be given with caution to patients with a history of gastrointestinal disease (e.g. ulcerative colitis, crohn's disease, hiatus hernia, gastro-oesophageal reflux disease, angiodysplasia) as the condition may be exacerbated.Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported. NSAID use should be discontinued at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity. Interactions:Use of two or more NSAID's concomitantly could result in an increase in side effects.Interaction between NSAID's and corticosteroids can cause an increased risk of gastrointestinal ulceration or bleeding (PUBs).Interaction between NSAID's and anti-platelet agents and selective serotonin reuptake inhibitors (SSRI's) can increase the risk of gastrointestinal bleeding.NSAID's may enhance the effects of anti-coagulants such as warfarin.Pregnancy and lactation:Nurofen is not recommended for use by pregnant women.Side-effects and special precautions:The most commonly observed adverse events are gastrointestinal in nature. Peptic ulcers, perforation or gastrointestinal bleeding, sometimes fatal. Nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, abdominal pain, melaena, haematemesis, ulcerative stomatitis, exacerbation of colitis and crohn's disease, gastritis.Dyspepsia, gastro-intestinal intolerance and bleeding may occur. Other side-effects include nervousness, skin rash, pruritis, tinnitus, oedema, hypertension and cardiac failure, depression, drowsiness, insomnia and blurred vision and other visual field defects. Hypersensitivity reactions, abnormalities of liver function tests, impairment of renal function, agranulocytosis, and thrombocytopenia have been observed. Acute reversible renal failure has been reported. Ibuprofen should be used with care in patients with impaired renal function.Bullous reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.Known symptoms of overdosage and particulars of its treatment:The most likely symptoms of over dosage are epigastric pain and nausea. If recently taken, gastric lavage will remove any unabsorbed ibuprofen. Electrolytes may be corrected by intravenous infusions, if necessary. There is no specific antidote to Nurofen.Keep out of reach of children.

Ingredients:
Ibuprofen 200mg Tablets