Pregnancy-safe retinol alternatives that actually work

Pregnancy can bring a wave of skin changes. Hormonal fluctuations often lead to breakouts, increased sensitivity, and pigmentation such as melasma. At the same time, experts usually recommend avoiding many powerful skincare actives, including retinol, as a precaution, leaving many women unsure about what they can safely use. 

The good news is that several ingredients can help address these concerns while keeping your routine pregnancy-friendly. According to biomedical scientist and skincare expert Dr Judey Pretorius, founder of Biomedical Emporium, ingredients such as bakuchiol, azelaic acid and peptides can help support healthier-looking skin without relying on vitamin A derivatives.

Why is retinol usually avoided during pregnancy?

Retinol has long been considered one of the most effective ingredients for improving skin texture, reducing fine lines and treating acne. However, it is generally avoided during pregnancy due to its connection to vitamin A.

“Retinoids are derivatives of vitamin A and are widely used for anti-ageing and acne treatment,” explains Dr Pretorius. “High levels of vitamin A have been linked to potential developmental risks during pregnancy. Although topical retinol is absorbed in very small amounts through the skin, most health care professionals recommend avoiding it during pregnancy as a precaution.”

Fortunately, other ingredients can help target many of the same skin concerns without the potential risks.

Pregnancy alternative: Bakuchiol 

Bakuchiol has quickly become one of the most popular alternatives to retinol. Derived from the seeds of the babchi plant, it offers similar benefits but is generally gentler on the skin. “Bakuchiol has gained attention as a plant-derived ingredient that can mimic some of the skin benefits of retinol, such as improving skin texture, reducing the appearance of fine lines and supporting collagen production,” says Dr Pretorius.

Unlike retinol, bakuchiol is not a vitamin A derivative, which is why it is often considered a suitable option during pregnancy. It is also less likely to cause irritation or dryness, making it a good option for those experiencing pregnancy-related sensitivity.

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Fundamentals Bakuchiol Serum 

Bioven Bakuchiol and Watermelon Radiance Hydrogel Eye Patches 

Nivea Cellular Expert Lift Serum

Sol Beauty Moisturising Rich Cream 

Pregnancy alternative: Azelaic Acid

Azelaic acid is another ingredient dermatologists often recommend during pregnancy, particularly for managing breakouts and pigmentation. “Azelaic acid is a versatile ingredient that helps reduce inflammation, control acne-causing bacteria and regulate excess pigmentation,” explains Dr Pretorius. 

It works by slowing down the production of melanin, which can help manage pregnancy-related pigmentation such as melasma. It can also help calm inflamed skin and reduce clogged pores. Because azelaic acid has very low systemic absorption, it is widely considered safe to use throughout all trimesters, making it a reliable option for treating both acne and uneven skin tone.

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The Ordinary Azelaic Acid 10 Suspension

Fundamentals 10 Azelaic Acid Serum

Pregnancy alternative: Peptides

While some stronger anti-ageing actives are avoided during pregnancy, ingredients that support the skin barrier and collagen production can still play an important role. Peptides are small chains of amino acids that act as building blocks for proteins in the skin. They help signal the skin to produce more collagen and support natural repair processes.

“Peptides are generally very well tolerated and can help maintain skin firmness and elasticity,” says Dr Pretorius. “During pregnancy, when stronger actives like retinoids are avoided, peptides can be a valuable way to support skin structure, hydration and overall skin health while keeping the routine gentle and balanced.”

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Skin Republic Multi Peptide + Ceremide Serum

Nip+Fab Replenish Peptide Fix Finishing Oil

Elizabeth Arden Hyaluronic Acid + Peptides Ceramide Capsules

Teaology Peptide Infusion Serum  

Understanding pregnancy-safe skincare

“A common misconception is that products labelled natural are automatically safe during pregnancy,” says Dr Pretorius. “Natural ingredients or essential oils can still cause irritation or may not be well researched for use during pregnancy.” Instead, she recommends focusing on well-studied ingredients that support the skin while remaining gentle. Options such as azelaic acid, niacinamide, peptides, hyaluronic acid and daily broad-spectrum sunscreen can help manage common pregnancy skin concerns. The key is to keep your routine simple and consistent. With the right ingredients, it is still possible to maintain healthy, balanced skin throughout pregnancy.

IMAGE: freepik.com