Doxylamine succinate

Doxylamine is an antihistamine.

Pronunciation: dox-IL-a-meen

What are doxylamine’s uses?

Doxylamine is used as a sleep aid, that is, as a short-term treatment for insomnia – this due to its sedative effects.

What dosage should you take?

As a sleeping aid, adults should take 25 to 50mg 30 minutes before bedtime.

However, always check the correct dosages with your Clicks pharmacist first.

What special precautions should you take?

  • It is not recommended for use in children under 12 years of age, so first consult with your doctor or Clicks pharmacist about paediatric use.
  • If you are pregnant or breastfeeding, first consult with your doctor about whether you can use doxylamine, as it could cause harm.
  • Be careful while driving, operating heavy machinery or doing anything that needs you to be alert as doxylamine can cause blurred vision and impaired thinking or reactions.
  • Do not drink alcohol when taking this antihistamine.
  • Doxylamine can decrease sweating and may make you more prone to heat stroke, so ensure you aren’t overheating or dehydrating during exercise and in hot weather while taking it.

Doxylamine should be avoided if you suffer from severe liver disease.

Doxylamine should be used with caution if you suffer from the following conditions (first consult with your doctor or Clicks pharmacist):

What drug interactions could you experience?

To avoid adverse drug interactions, always inform your doctor or Clicks pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements and herbal products you are taking or planning to take.

What are doxylamine’s side effects?

Its side effects could include:

  • Long-lasting impaired consciousness in children
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Decreased coordination
  • Confusion
  • Headache
  • Constipation
  • Upset stomach
  • Dry mouth, nose or throat
  • Speech difficulties
  • Hair loss

This is not a complete list of side effects. It’s essential that you call your doctor should you notice any severe or odd side effects.

What are the overdose symptoms?

Call your doctor or the ambulance immediately if you notice the following overdose symptoms:

  • Large pupils
  • Flushing
  • Fever
  • Confusion
  • Hallucinations
  • Tremors
  • Loss of consciousness
  • Seizures
  • Signs of an allergic reaction like hives, difficulty breathing, swelling of your face, etcetera
The accuracy of this information was checked and approved by Clicks' pharmacist Waheed Abdurahman in April 2015