Grape seed extract

Grape seed extract is an industrially-produced derivative of grape seeds, found to be rich in antioxidants.

What are its health benefits?

Grape seed extract has been associated with a range of possible therapeutic properties including wound healing, and assisting in the management of conditions such as macular degeneration, high cholesterol, nerve damage and poor circulation.

While evidence is emerging of its health benefits, many still need to be supported with further study. 

Grape seed extract supplementation may have the following benefits:

  • Aids the wound healing process
  • Supports bone health when taken in conjunction with calcium
  • Assists in the protection of blood vessels from becoming damaged
  • Assists in reducing swelling (edema) that occurs after injury or surgery (for example, breast cancer surgery)
  • May assist with prevention of a decline in memory and thinking abilities associated with ageing

Recommended dietary allowance (RDA)

There is no established RDA for grape seed extract, nor has a safety protocol been established on the highest dose. In studies, daily doses have generally been between 100 to 300mg.


Grape seed extract is not recommended for children, during pregnancy or breastfeeding.

Those with grape allergies should avoid using this supplement

If you’re taking heart medication, blood thinners, cancer medication or nonsteroidal anti-inflammatory drugs (NSAIDs), consult your doctor or Clicks pharmacist before taking grape seed extract.

Possible side effects

Side effects could include:

  • Headache
  • Nausea
  • Dizziness
  • Itchy scalp

Ensure you discuss dietary supplementation with your Clicks pharmacist to avoid the potential for side effects and adverse interactions with medications.

This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to diagnose, treat, cure or prevent any disease.

The accuracy of this information was checked and approved by Clicks' pharmacist Waheed Abdurahman in September 2015