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Skinoren

Cream 30g

Skinoren Acne Cream 30g contains active ingredients including AzelaicAcid.

R 27200

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dispensed by pharmacist

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Otc Product Info

Description:
Skinoren Acne Cream 30g

Detailed Description:
1g cream contains azelaic acid 0.2g/g.Benzoic acid 0.2% (m/m).Patient information leaflet:Scheduling status: S1.Proprietary name and dosage form:What Skinoren acne cream is used for:Skinoren Acne cream is used for the treatment of mild to moderate acne.Presentation of Skinoren acne cream:Tubes of 10, 20, 30 or 50g. The tubes are made of aluminium and screw cap are made of high density polyethylene.Identification of Skinoren acne cream:White to slightly yellowish opaque cream.Scheduling status: S1.Proprietary name and dosage form:Skinoren acne cream:Anti-acne agent.Composition:1g Skinoren acne cream contains 200 mg azelaic acid.Pharmacological classification:A 13.12 acne preparations.Pharmacological action:Pharmacodynamic properties:The antimicrobial property of azelaic acid and a direct influence on follicular hyperkeratosis are assumed to be the basis for the therapeutic efficacy of Skinoren acne cream in acne.Clinically, a significant reduction of the colonisation density of propionibacterium acnes and a significant reduction in the fraction of free fatty acids in the skin surface lipids is observed.In vitro and in vivo, azelaic acid inhibits the proliferation of keratinocytes and normalises the disturbed terminal epidermal differentiation processes in acne. In the rabbit ear model azelaic acid accelerates the comedolysis of tetradecane-induced comedones.Pharmacokinetics:Azelaic acid penetrates into all layers of human skin after topical application of the cream. Penetration is faster into damaged skin than into intact skin. A total of 3.6% of the dose applied is absorbed percutaneously after a single topical application of 1g azelaic acid (5g cream).A portion of the azelaic acid absorbed through the skin is excreted in unchanged form with the urine. The remaining portion is broken down by R-oxidation into dicarboxylic acids with shorter chain length (C7, C5) which have likewise been found in the urine.Indications:Topical treatment of mild to moderate acne vulgaris.Identification:White to slightly yellowish opaque cream.Presentation:Tubes of 10, 20, 30 or 50g. The tubes are made of aluminium and screw caps are made of high density polyethylene.

Pack size:
30g

Quantity in pack:
1

Marketing description:
Bayer.S1.Skinoren®.Acne cream.20%.30g.

Brand:
Skinoren

Package type:
Box

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Usage instructions:
How to use Skinoren acne cream:Do not share medicines prescribed for you with others.Before Skinoren acne cream is applied, the skin should be thoroughly cleaned with plain water and dried. A mild skin-cleansing agent may be used.Skinoren acne cream should be applied to the affected skin areas twice a day (morning and evening) and rubbed gently into the skin.The amount of Skinoren acne cream to be applied will depend on the size of the affected area.In the event of intolerable irritation of the skin (see "possible side effects"), the amount of Skinoren acne cream per application should be reduced or the frequency of use of Skinoren acne cream should be reduced to once a day until the irritation ceases. If required, the treatment should be temporarily interrupted for a few days.The duration of use of Skinoren acne cream can vary from person to person and also depends on the severity of the skin disorder. In general, an improvement becomes apparent after about 4 weeks. To obtain the best results, however, Skinoren acne cream should be used continuously over several months.There is clinical experience for a continuous application time period up to one year.Dosage and directions for use:Skinoren acne cream should be applied to the affected areas of the skin twice a day (mornings and evenings) and rubbed in gently.Approximately 2.5 cm of cream is sufficient for the entire facial area.Before Skinoren acne cream is applied, the skin should be thoroughly cleaned with plain water and dried. A mild skin-cleansing agent may be used.It is important to continue to use Skinoren acne cream regularly over the entire period of treatment.The duraton of use of Skinoren acne cream can vary from patient to patient and also depends on the severity of the acne. In general, an improvement of the condition becomes apparent after about 4 weeks. To obtain the best results, Skinoren acne cream should be used continuously over several months. There is clinical experience for a continuous application time period up to one year.In the event of intolerable skin irritation (see "side effects and special precautions"), the amount of cream per application should be reduced or the frequency of use of Skinoren acne cream should be reduced to once a day until the irritation ceases. If required, treatment might have to be temporarily interrupted for a few days.Paediatric population:Use in adolescents (12 to 18 years of age). Dose adjustment is not required when Skinoren acne cream is administered to adolescents aged 12 to 18 years.The safety and efficacy of Skinoren acne cream in children below the age of 12 years have not been established.

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Ingredients:
Patient Information Leaflet:What Skinoren acne cream contains:The active substance is Azelaic Acid. 1 gram Skinoren acne cream contains 200 mg Azelaic Acid.The Other Ingredients are: Arlatone 983 S; Cutina CBS; Cetearyloctanoate; Propylene Glycol; Glycerol 85%; Purified Water and Benzoic Acid (0.2% m/m) as a Preservative.Skinoren Acne Cream contains the following excipients:Arlatone 983 S; Cutina CBS; Cetearyl Octanoate (PCL Liquid); Propylene Glycol; Glycerol 85%; Benzoic Acid and Purified Water.

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