Naphazoline (naphazoline hydrochloride)

Naphazoline is a decongestant.

Pronunciation: Na-FAZ-oh-leen

What are naphazoline’s uses?

Naphazoline is used in nasal sprays to treat symptoms of nasal congestion and in eye drops to treat red eyes, eye irritation and symptoms of pink eye.

Its uses include clearing redness and relieving scratchiness in the eye caused by irritants, and it eases nasal congestion caused by colds, flu, hay fever and allergies.

What dosage should you take?

Eye drops dosage: Instill one or two drops in the conjunctival sac(s) every three to four hours as needed.

For your nose, spray into the open nostril three to four times a day. Do not use this medication for longer than three to five days at a time.

However, first check the correct dosages with your Clicks pharmacist.

What special precautions should you take?


  • If you wear contact lenses, remove them before you apply naphazoline. Wait for at least 15 minutes after putting the drops into your eye before reinserting your lenses.
  • Speak to your doctor if eye redness or irritation is not resolved in 48 hours.
  • If you are using other eye drops, do not use one immediately after the other.
  • Its use is considered safe during pregnancy or while breastfeeding, however do consult your doctor first.

Drops should be used with caution if you suffer from the following conditions:


  • Long-term use is not recommended. Don’t use for more than five days or it may cause a condition called rebound congestion.
  • Avoid spraying into your eyes or onto the middle of the inside of your nose.
  • It is not known to cause any problems during pregnancy or while breastfeeding.

Use with caution if you have any of the following health problems:

What drug interactions could you experience?

As a rule, always inform your doctor or Clicks pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements and herbal products you are taking or planning to take to ensure you don’t suffer the effects of adverse drug interactions.

What are naphazoline’s side effects?

Side effects could include:

  • Blurred vision
  • Stinging
  • Severe allergic reactions
  • Eye pain
  • Persistent eye irritation
  • Dilated pupils


  • Temporary burning
  • Stinging
  • Dry nose
  • Runny nose
  • Sneezing

This is not a complete list of side effects. It’s essential that you call your doctor should you notice any severe or odd side effects.

What are the overdose symptoms?

Call a doctor or the ambulance immediately if you notice the following symptoms:

  • Pounding heartbeat
  • Dizziness
  • Nausea
  • Headache
  • Mood changes
  • Trouble sleeping
  • Tremors
  • Profuse sweating
The accuracy of this information was checked and approved by Clicks' pharmacist Waheed Abdurahman in August 2015