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34914

Laxette

Dry 10 Sachets

Laxette Dry 10 Sachets is an easy-to-use laxative with 10 mg lactulose to help provide predictable relief for constipation. Mixed with water or juice it’s easy to drink and expands when reaching the colon to assist with peristalsis and naturally and effectively expel waste.

R 6299
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Description:
Laxette Dry Symptomatic Treatment Of Constipation 10 Sachets

Detailed Description:
Scheduling status: Not scheduled. Proprietary name (and dosage form): Laxette dry (crystalline powder). Laxette (solution). Composition: Each sachet Laxette dry contains: 10g lactulose. Each 5ml Laxette contains: 3.3g lactulose. Pharmacological classification: A 11.5 laxatives. Pharmacological Action: Lactulose is a synthetic disaccharide of fructose and galactose. It reaches the colon unchanged where it is broken down by the colonic bacteria, mainly into lactic acid, which produces an osmotic effect in the colon, resulting in increased faecal bulk and stimulation of colonic peristalsis. The increased acid production of larger doses of lactulose, as given for hepatic encephalopathy, reduces the pH in the colon significantly and the absorption of ammonium ions and other toxic nitrogenous compounds are decreased, leading to a fall in blood-ammonium levels. Pharmacokinetics: After oral administration, lactulose passes essentially unchanged into the large intestine where it is metabolised by saccharolytic bacteria into simple organic acids, mainly lactic acid and small amounts of formic and acetic acids. A small amount of lactulose is absorbed and is excreted unchanged in the urine. Indications: Lactulose is used in the management of constipation, particularly in association with laxative habituation and in post-surgical and obstetric patients, as well as in children. For the management of hyperammonaemia in patients with chronic hepatic encephalopathy, including stages of hepatic pre-coma and coma. Known symptoms of overdosage and particulars of its treatment: See side-effects and special precautions. Prolonged use or excessive dosage may result in diarrhoea, with excessive loss of water and electrolytes. Treatment is symptomatic and supportive. Identification: Laxette dry: A white crystalline powder. Laxette solution: A colourless to brownish - yellow solution with a sweet taste. Presentation: Laxette dry: 10 g sachets in packs of 10 or 30 per carton box. Laxette solution: 150 ml and 500 ml amber glass bottles.

Pack size:
10 sachets

Quantity in pack:
10

Marketing description:
Symptomatic treatment of constipation. Laxette dry. Each sachet contains: lactulose 10g. Cipla. We'll make it better. 10 sachets.

Brand:
Laxette

Package type:
Box

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Usage instructions:
Dosage and directions for use: An effect may only be obtained after 24 - 48 hours. Laxette dry: Constipation: Drink a full glass of liquid or more, with each dose of lactulose. Adults: Initial dose - 10 to 30 g given daily as a single dose or in 2 divided doses for three (3) days. Maintenance dose - Adjust according to the patient's needs. Dosage may be increased to 40 g daily if there is no response, or should be decreased if diarrhoea occurs. Children (7-14 years): Usual dosage - 10 g taken daily. Dosage should be adjusted according to individual response. Children (1- 6 years): Usual dosage - 5 to10 g taken daily. Dosage should be adjusted according to individual response. Portal System Encephalopathy: Drink a full glass of liquid or more, with each dose of lactulose. Initial dosage - 60 to 120 g given daily in 3 or 4 divided doses. Maintenance dose - Dosage should be adjusted to produce 2 or 3 soft stools each day. Laxette dry can be taken with drinks eg. tea, coffee, fruit juice or milk, or with breakfast cereals. Laxette solution: Constipation: Initial dose should be taken for three (3) days in all age groups. Adults: Usual initial dose - 30 ml. Maintenance dose - 15 - 30 ml. Children (6 - 14 years): Usual initial dose - 15ml. Maintenance dose - 10 - 15 ml. Children (1 - 5 years): Usual initial dose - 10ml. Maintenance dose - 5 - 10 ml. Infants: Usual initial dose - 5ml. Maintenance dose - 2.5 - 5ml. Portal System encephalopathy: Initial dose - 30 - 50 ml three times daily. Subsequently adjust the dose to produce two or three soft stools daily.

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