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Detailed information
Description:
Infections 1and2 Mouth And Lip Care Fenivir Cold Sore Cream 2g
Detailed Description:
2 g cream/room.Scheduling status:S1.Proprietary name (and dosage form):Fenivir® cold sore cream.Composition:1 g of cream contains 0.01 g penciclovir.Contains 41.68 % m/m propylene glycol as preservative.Pharmacological classification:A 20.2.8 antiviral agents.Pharmacological action:Penciclovir has demonstrable in vitro activity against herpes simplex viruses (types 1 and 2), varicella-zoster virus and epstein-barr virus. Some in vitro activity against cytomegalovirus has been demonstrated against herpes simplex virus (types 1 and 2) infections in animals. Penciclovir targets virus-infected cells where it is converted into a triphosphate (mediated via virus-induced thymidine kinase). This triphosphate persists in infected cells in excess of 12 hours and inhibits replication of viral DNA. In uninfected cells treated with penciclovir, concentrations of penciclovir triphosphate are only barely detectable. Accordingly, uninfected cells are unlikely to be affected by therapeutic concentrations of penciclovir.Indications:Fenivir cold sore cream is indicated for the treatment of cold sores.Fenivir cold sore cream shortens healing time, reduces lesion-associated pain and shortens the duration of viral shedding.Identification:A smooth white homogeneous cream.Presentation:2 g aluminium tube.Marketed by: Novartis Consumer Health SA A division of Novartis South Africa (Pty) Limited.Novartis.For full prescribing information please read the enclosed package insert.011 929 9111.
Pack size:
2g
Quantity in pack:
1
Marketing description:
Antimicrobials anti-viral agents.
Brand:
Fenivir
How to use
Storage instructions:
Store at temperatures not exceeding 30 degrees C. Do not freeze.Keep well closed.
Warnings:
Contra indications:Known hypersensitivity to penciclovir, famciclovir, or any of the constituents, e.g. propylene glycol.Side effects and special precautions:Transient burning, stinging and numbness has occurred infrequently on application.Special precautions:Fenivir cold sore cream should only be used on cold sores on the lips and face. Not recommended for application to mucous membranes.Particular care should be taken to avoid application in or near the eye.Pregnancy and lactation:Systemic absorption of penciclovir following topical administration of Fenivir cold sore cream has been shown to be minimal. However since the safety of penciclovir in human pregnancy has not been established, Fenivir cold sore cream should not be used during pregnancy or in nursing mothers.Keep out of the reach of children.