Clotrimazole is an active ingredient in many antifungal medications.

Pronunciation: kloe-TRIM-uh-zole

What are clotrimazole’s uses?

Clotrimazole is used to treat fungus infections of the skin, specifically candida, which includes athlete’s foot, ringworm, oral or vaginal thrush. It works by killing the fungus, Candida albicans, that causes the infection.

What dosage should you take?

The typical dosage is to apply the cream two to three times a day for one to four weeks. Your Clicks pharmacist will advise the length of time.

Clotrimazole may be prescribed in pessary or cream form for vaginal thrush. In pessary or vaginal cream form, it is commonly prescribed as once a day for one week, but there are single dose preparations available as well.

Topical application of Clotrimazole is safe for children.

What special precautions should you take?

  • Tell your doctor or Clicks pharmacist if you are taking antibiotics or any other medications.
  • Tell your doctor or Clicks pharmacist about your medical history.
  • Do not share clotrimazole cream with anyone, as you may spread the infection, and do not use the same cream for a later infection. Discard after your condition has cleared up. (Consult your Clicks pharmacist about the best way to dispose of unused medication.)
  • Store clotrimazole cream at room temperature and keep away from heat or sun.
  • It is important to keep taking clotrimazole for the full time prescribed, even if symptoms appear to have cleared up.
  • Rather avoid its use while you are pregnant or breastfeeding. Use only if your doctor has determined that the benefits outweigh the risks.

Clotrimazole should be used with caution if you have the following conditions:

  • Porphyria (a group of rare genetic disorders that affect mainly the skin or nervous system)
  • A history of liver disease
  • Diabetes

What drug interactions could you experience?

To avoid adverse drug interactions, always inform your doctor or Clicks pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements and herbal products you are taking or are planning to take.

What are clotrimazole’s side effects?

Side effects may include:

  • Burning
  • Itching
  • Swelling
  • Redness
  • Irritation

If your symptoms worsen after applying clotrimazole cream, discontinue use and consult your doctor.

This is not a complete list of side effects. It’s essential that you call your doctor should you notice any severe or odd side effects.

If any of the following severe symptoms occur, seek medical attention immediately:

  • Hives
  • Swelling of the eyes, lips and/or tongue
  • Difficulty breathing
  • Fever/chills
  • Severe itching and/or burning

What are the overdose symptoms?

Common side effects of an overdose of the clotrimazole lozenges include:

If you suspect an overdose, seek medical attention immediately.

The accuracy of this information was checked and approved by Clicks' pharmacist Waheed Abdurahman in April 2015